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The Theory of Response-Adaptive Randomization in Clinical Trials
Feifang Hu
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Description for The Theory of Response-Adaptive Randomization in Clinical Trials
Hardcover. In this well written book, the authors treat the fundamental question of response-adaptive randomization as dealing with the trade-off between minimizing the expected number of treatment failures and maximizing the power of inferential tests. Series: Wiley Series in Probability and Statistics. Num Pages: 232 pages, Illustrations. BIC Classification: MB; PB. Category: (P) Professional & Vocational. Dimension: 243 x 166 x 19. Weight in Grams: 488.
Presents a firm mathematical basis for the use of response-adaptive randomization procedures in practice
Presents a firm mathematical basis for the use of response-adaptive randomization procedures in practice
The Theory of Response-Adaptive Randomization in Clinical Trials is the result of the authors' ten-year collaboration as well as their collaborations with other researchers in investigating the important questions regarding response-adaptive randomization in a rigorous mathematical framework. Response-adaptive allocation has a long history in biostatistics literature; however, largely due to the disastrous ECMO trial in the early 1980s, there is a general reluctance to use these procedures.
This timely book represents a mathematically rigorous subdiscipline of experimental design involving randomization and answers fundamental questions, including:
... Read moreProduct Details
Format
Hardback
Publication date
2006
Publisher
John Wiley & Sons Inc United States
Number of pages
232
Condition
New
Series
Wiley Series in Probability and Statistics
Number of Pages
232
Place of Publication
, United States
ISBN
9780471653967
SKU
V9780471653967
Shipping Time
Usually ships in 7 to 11 working days
Ref
99-50
About Feifang Hu
FEIFANG HU, PhD, is Associate Professor in the Department of Statistics at the University of Virginia. He is the recipient of numerous grants, honors, and awards. His research interests include biostatistics, applied probability and statistical inference, and resampling methods. He has authored over forty refereed articles. WILLIAM F. ROSENBERGER, PhD, is Professor and Chair of the Department of Applied ... Read more
Reviews for The Theory of Response-Adaptive Randomization in Clinical Trials
"The book provides a comprehensive overview of the theory of repsonse-adaptive radomization and is recommended to readers with an interest in this specialist area." (Statistics in Medicine, July 2008) "I can recommend this book for the intended target audience which will include industry statisticians with a special interest in this area." (Pharmaceutical Statisitcs, 2008) "…this ground-breaking text ... Read more