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The Quest for the Cure: The Science and Stories Behind the Next Generation of Medicines

Brent Stockwell

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Description for The Quest for the Cure: The Science and Stories Behind the Next Generation of Medicines Hardback. After more than 50 years of blockbuster drug development, skeptics fear we may be reaching the end of drug discovery to combat major diseases. A leading researcher in the exciting new science of chemical biology describes this dilemma and the powerful techniques that may bring drug research into the 21st century. Num Pages: 284 pages, 4 color illus., 18 line drawings. BIC Classification: MMG; PSB. Category: (P) Professional & Vocational. Dimension: 210 x 140 x 24. Weight in Grams: 442.
After more than fifty years of blockbuster drug development, skeptics are beginning to fear we are reaching the end of drug discovery to combat major diseases. In this engaging book, Brent R. Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and the powerful techniques that may bring drug research into the twenty-first century. Filled with absorbing stories of breakthroughs, this book begins with the scientific achievements of the twentieth century that led to today's drug innovations. We learn how the invention of mustard gas in World War I led to early anti-cancer ... Read more

Product Details

Format

Hardback

Publication date

2011

Publisher

Columbia University Press

Condition

New

Number of Pages

284

Place of Publication

New York, United States

ISBN

9780231152129

SKU

V9780231152129

Shipping Time

Usually ships in 7 to 11 working days

Ref

99-1

About Brent Stockwell

Brent R. Stockwell is an associate professor of biological sciences and chemistry at Columbia University and a Howard Hughes Medical Institute Early Career Scientist. He serves on the editorial board of Chemistry & Biology, has been awarded ten U.S. patents, and has published fifty-four scientific papers. Among his recent honors are a Burroughs Wellcome Fund Career Award at the Scientific ... Read more

Reviews for The Quest for the Cure: The Science and Stories Behind the Next Generation of Medicines

The dearth of promising new treatments for many a serious disease remains a major challenge not just for the pharmaceutical industry but for all of society. In this exhaustively researched book, Brent R. Stockwell surveys the history of drug development and offers insightful suggestions for innovative new approaches. This is critical reading for the many involved in and concerned about ... Read morethis urgent issue.
Robert Bazell, chief science correspondent, NBC News, and author of Her-2: The Making of Herceptin, a Revolutionary Treatment for Breast Cancer This is a terrific book! Stockwell's writing is clear and engaging as he presents a thoughtful analysis of drug development that can be understood and appreciated by a diverse readership. Stockwell beautifully combines scientific history and personal anecdotes with clear explanations of the principles and practices of chemical biology to make a fascinating story of the past, present, and future of drug discovery. His book is informative, accurate, and a good read all put together.
Geoffrey Cooper, Boston University, author of The Cell: A Molecular Approach and Oncogenes This is a truly wonderful book. Stockwell's writing will open the door to a universe that many readers may know little about. Drugs are born, biotech companies are created, scientists' careers are made and unmade, egos are raised and dashed. This book is so readable, it is an absolute page-turner. Yet it is also authoritative and scientifically sophisticated, managing to distill a complex, changing field into a beautifully written, well-crafted story.
Siddhartha Mukherjee, Columbia University, author of The Emperor of All Maladies: A Biography of Cancer By providing accessible explanations for the underlying biological and chemical principles that apply to the complex solutions he describes, Stockwell enables even the scientifically unsophisticated reader to gain a wider perspective on what future disease treatment might entail. Publishers Weekly This very readable, even exciting work takes us through the medical breakthroughs of the past century. Globe and Mail This book deserves a readership, and there is certainly a need for it. As a drug companyresearcher, I have often wished that more people understood what the field was likeand how simultaneously fascinating and frustrating it can be.
Derek B. Lowe Cell In this well-researched look into the complexities of making medicines, a chemical biologist gives a history of drug making and details innovative methods of drug discovery. Science News Despite our current political paralysis, government leaders should listen to Stockwell and be certain to advance our capacity to generate the drugs that our society and the world need. Harvard Magazine The book is well organized and includes many interesting, clever analogies to explain what can be complicated scientific problems. Choice An engaging and rewarding read...
Donald C. Lo Journal of Clinical Investigation The reader is not only left with a satisfying overview of the proud history and future challenges of finding new medicines but also encouragement that Stockwell and his contemporaries are creatively committed to academic drug discovery.
David Kroll Nature Chemistry Stockwell writes well-his prose is accessible to the educated reader, irrespective of his or her background. All of the personalities, errors and successes in contemporary drug discovery are presented. Stockwell enlivens their stories with anecdotes...
Garrett A. FitzGerald Nature Medicine It is impossible to read this relatively short book...without being captured by the author's optimism about the future of drug development.
Robert C. Young, M.D. Oncology Times Show Less

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The Quest for the Cure: The Science and Stories Behind the Next Generation of Medicines

Brent Stockwell

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