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Angiogenesis and Anti-Angiogenesis in Hematological Malignancies
Domenico Ribatti
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Description for Angiogenesis and Anti-Angiogenesis in Hematological Malignancies
Hardcover. Angiogenesis and Anti-Angiogenesis in Hematological Malignancies Num Pages: 114 pages, 14 black & white illustrations, 30 colour illustrations, 8 black & white tables, biograph. BIC Classification: MJCL; MJF; PSA. Category: (P) Professional & Vocational. Dimension: 241 x 162 x 13. Weight in Grams: 374.
It has been generally accepted that angiogenesis is involved in the pathogenesis of hematological malignancies, like acute and chronic leukemia, lymphoma, myelodysplastic syndromes, myeloproliferative neoplasms and multiple myeloma. The extent of angiogenesis in the bone marrow has been correlated with disease burden, prognosis and treatment outcome. Reciprocal positive and negative interactions between tumor cells and bone marrow stromal cells, namely hematopoietic stem cells, fibroblasts, osteoblasts/osteoclasts, endothelial cells, endothelial progenitor cells, T cells, macrophages and mast cells, mediated by an array of cytokines, receptors and adhesion molecules, modulate the angiogenic response in hematological tumors. More recently, it has been emphasized the ... Read more
It has been generally accepted that angiogenesis is involved in the pathogenesis of hematological malignancies, like acute and chronic leukemia, lymphoma, myelodysplastic syndromes, myeloproliferative neoplasms and multiple myeloma. The extent of angiogenesis in the bone marrow has been correlated with disease burden, prognosis and treatment outcome. Reciprocal positive and negative interactions between tumor cells and bone marrow stromal cells, namely hematopoietic stem cells, fibroblasts, osteoblasts/osteoclasts, endothelial cells, endothelial progenitor cells, T cells, macrophages and mast cells, mediated by an array of cytokines, receptors and adhesion molecules, modulate the angiogenic response in hematological tumors. More recently, it has been emphasized the ... Read more
Product Details
Format
Hardback
Publication date
2014
Publisher
Springer
Condition
New
Number of Pages
114
Place of Publication
Dordrecht, Netherlands
ISBN
9789401780346
SKU
V9789401780346
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Angiogenesis and Anti-Angiogenesis in Hematological Malignancies
From the reviews: “This book will appeal mainly to researchers in the field of angiogenesis/antiangiogenesis, and students. … This is a comprehensive book on an important area of cancer research that is often overshadowed by literature on solid tumors. It will be most helpful for researchers looking for information on the subject, but it also enlightens practitioners on the ... Read more