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Jean-Paul Renaud - Structural Biology in Drug Discovery: Methods, Techniques, and Practices - 9781118681015 - V9781118681015
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Structural Biology in Drug Discovery: Methods, Techniques, and Practices

€ 287.41
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Description for Structural Biology in Drug Discovery: Methods, Techniques, and Practices Hardcover. With the most comprehensive and up-to-date overview of structure-based drug discovery and using experimental and computational approaches, this book covers principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Num Pages: 448 pages. BIC Classification: PN; PS; TDCW. Category: (P) Professional & Vocational. Dimension: 185 x 135 x 5. .

With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field.

The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that:

  • Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray ... Read more
  • Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design
  • Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures
  • Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins
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Product Details

Format
Hardback
Publication date
2020
Publisher
John Wiley & Sons Inc United States
Number of pages
448
Condition
New
Number of Pages
688
Place of Publication
New York, United States
ISBN
9781118681015
SKU
V9781118681015
Shipping Time
Usually ships in 7 to 11 working days
Ref
99-11

About Jean-Paul Renaud
JEAN-PAUL RENAUD, PhD, is cofounder and President & Chief Scientific Officer at Urania Therapeutics (formerly RiboStruct), which focuses on rational drug design targeting the human ribosome. Previously, he was cofounder and Chief Scientific Officer at NovAliX and CNRS Research Director in the Structural Biology and Genomics Department at the Institute of Genetics and Molecular and Cellular Biology. Dr Renaud has ... Read more

Reviews for Structural Biology in Drug Discovery: Methods, Techniques, and Practices
"The book ... is a surprisingly comprehensive, monumental collection of chapters by a number of researchers in the field of drug discovery. ... [Editor Jean-Paul] Renaud was able to see the broad crucial aspects of the field and therefore able to invite excellent scientists to coauthor this book and cover so many aspects and in so much depth."
Crystallography ... Read more

Goodreads reviews for Structural Biology in Drug Discovery: Methods, Techniques, and Practices


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